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B12 is typically administered intramuscularly into the deltoid (upper arm) or the gluteal muscle

Adults with type 2 diabetes and obesity lose less weight on EVERY GLP-1 drug compared to those without diabetes, consistently ~5% less

These vascular benefits may stem from both systemic improvements and direct effects on the vasculature, given the expression of GLP-1 receptors in both vascular smooth muscle and endothelial cells 55

It functions by increasing telomerase activity, an enzyme responsible for elongating and maintaining telomere length

They can effectively activate GPER without affecting other estrogen receptors (including ER and ER) [250]